Data Structure ?
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Data Structure ?
*The above analysis is the result extracted and analyzed by the system, and the specific actual data shall prevail.
README.md
新しい参照ゲノムのシーケンシングと計算によるアセンブリのスピードが加速しています。DNAシーケンシング技術とアセンブリソフトウェアツールが絶えず改善されているにもかかわらず、ゲノムの生物学的特徴（繰り返し配列や通常はシーケンシングライブラリーの調製に伴う分子アーチファクトなど）は、断片化またはキメラアセンブリを引き起こす可能性があります。このような欠陥を修正しない場合、ゲノムの構造と機能の理解に進展が見られるかもしれませんが、さらに悪いことに、この研究を誤導することは確実です。幸いなことに、マーカーが密集した遺伝地図や関連分類群における保存された相同遺伝子の順序など、追加の独立した情報を統合することで、未連結、無秩序な断片を構築し、誤って連結された参照ゲノムを再構築することができます。私たちはこれらのプロセスを自動化するツールセットを提供しています。このツールセットは、アセンブリと遺伝地図の変化を追跡することもでき、ユーザーがWebベースのグラフィック可視化を利用してこれらの変化を詳細に調べることを可能にします。Chromonomerは、ユーザーが定義した参照ゲノム、遺伝マーカー地図、および（オプションで）保存された共線情報を用いて、改善された染色体モデル参照ゲノム「クロモノーム」を構築します。私たちは、さまざまな特徴と品質レベルを持つゲノムアセンブリと遺伝地図におけるクロモノマーの性能を示します。
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